GUILLAIN-BARRE SYNDROME

What is Guillain-Barre Syndrome (GBS)?

Guillain-Barre Syndrome is an inflammatory disorder of the peripheral nerves.  The characteristics include the onset (which can be very rapid) of weakness and often paralysis of the legs, arms, breathing muscles and face.  It came to public attention in 1976 and thousands of people are newly diagnosed every year.  GBS can affect any person at any age.

The cause of GBS isn't known, but 50% of cases appear to occur shortly after an infection such as a sore throat of diarrhea.  One idea is that the autoimmune system of antibodies and white blood cells is triggered into damaging the nerve covering or insulation, which leads to weakness and abnormal sensation.

Progression of the diesease in the early stages is unpredicatable, so most newly diagnosed patients are hospitalized.  Care involves use of general supportive measures for the paralyzed patient, and also methods specifically designed to speed recovery, especially for those patients with major problems, such as the inability to walk.